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  • Single-Arm Phase II Survival Trial Design
    Single-Arm Phase II Survival Trial Design

    Single-Arm Phase II Survival Trial Design provides a comprehensive summary to the most commonly- used methods for single-arm phase II trial design with time-to-event endpoints.Single-arm phase II trials are a key component for successfully developing advanced cancer drugs and treatments, particular for target therapy and immunotherapy in which time-to-event endpoints are often the primary endpoints.Most test statistics for single-arm phase II trial design with time-to-event endpoints are not available in commercial software.Key Features: Covers the most frequently used methods for single-arm phase II trial design with time-to-event endpoints in a comprehensive fashion. Provides new material on phase II immunotherapy trial design and phase II trial design with TTP ratio endpoint. Illustrates trial designs by real clinical trial examples Includes R code for all methods proposed in the book, enabling straightforward sample size calculation.

    Price: 45.99 £ | Shipping*: 0.00 £
  • Universal Trial
    Universal Trial


    Price: 24.99 £ | Shipping*: 3.99 £
  • The Trial
    The Trial

    On the day after his thirtieth birthday, Josef K, a bank teller, is arrested by two mysterious agents of an unspecified organization.Confused and shocked, Josef inquires about the crime he is being accused of, but the agents will not answer, leaving Josef to decide what he feels most guilty for.Though he is not imprisoned, Josef is told to await further instructions.Tortured by the unknown, Josef returns to his home and tries to guess what he could be charged for.His landlady, Frau Grubach, feels amicably about Josef despite the arrest and wishes to help.She speculates that he is likely being punished for his promiscuous behavior involving one of his neighbors.Josef is unable to confirm this, but he does go to his neighbor, Fraulien, for comfort.While she does accept his affection and kiss at first, Fraulien later rejects Josef’s advances.When he returns home, he is given unclear instructions for his court appearance.With an address, but not a specific report time, Josef arrives late to his trial, angering the assembly.When Josef vents his frustrations about the absurdity of the trial, he upsets the court even more.Still unclear on the charges he faces and the possible punishment, Josef feels the weight of guilt and the immeasurable high stakes as the trial proceeds.While he is thrown in a whirlwind of chaos and uncertainty, Josef pleas his innocence as he still investigates what crime he is being tried for. Through brilliant symbolism and excellent characterization, The Trial by Franz Kafka is an intelligent and intriguing perspective on the innerworkings of the justice system, told from the point of view of the guilty or accused.Published posthumously in 1925, The Trial has become one of Franz Kafka’s most popular works, and has been adapted for film, radio, and theater.With several interpretations and possible meanings, Franz Kafka’s The Trial provides a thrilling and thought-provoking reading experience for contemporary audiences.This edition of The Trial by Franz Kafka is accessible for modern readers with features such as its new, striking cover design and the stylish, readable font it is printed in.

    Price: 14.99 £ | Shipping*: 3.99 £
  • The Trial
    The Trial

    On the day after his thirtieth birthday, Josef K, a bank teller, is arrested by two mysterious agents of an unspecified organization.Confused and shocked, Josef inquires about the crime he is being accused of, but the agents will not answer, leaving Josef to decide what he feels most guilty for.Though he is not imprisoned, Josef is told to await further instructions.Tortured by the unknown, Josef returns to his home and tries to guess what he could be charged for.His landlady, Frau Grubach, feels amicably about Josef despite the arrest and wishes to help.She speculates that he is likely being punished for his promiscuous behavior involving one of his neighbors.Josef is unable to confirm this, but he does go to his neighbor, Fraulien, for comfort.While she does accept his affection and kiss at first, Fraulien later rejects Josef’s advances.When he returns home, he is given unclear instructions for his court appearance.With an address, but not a specific report time, Josef arrives late to his trial, angering the assembly.When Josef vents his frustrations about the absurdity of the trial, he upsets the court even more.Still unclear on the charges he faces and the possible punishment, Josef feels the weight of guilt and the immeasurable high stakes as the trial proceeds.While he is thrown in a whirlwind of chaos and uncertainty, Josef pleas his innocence as he still investigates what crime he is being tried for. Through brilliant symbolism and excellent characterization, The Trial by Franz Kafka is an intelligent and intriguing perspective on the innerworkings of the justice system, told from the point of view of the guilty or accused.Published posthumously in 1925, The Trial has become one of Franz Kafka’s most popular works, and has been adapted for film, radio, and theater.With several interpretations and possible meanings, Franz Kafka’s The Trial provides a thrilling and thought-provoking reading experience for contemporary audiences.This edition of The Trial by Franz Kafka is accessible for modern readers with features such as its new, striking cover design and the stylish, readable font it is printed in.

    Price: 7.99 £ | Shipping*: 3.99 £
  • Search for an anime with adventure, action, and fantasy elements.

    One anime that fits this description is "Fullmetal Alchemist: Brotherhood." This series follows two brothers, Edward and Alphonse Elric, as they search for the Philosopher's Stone to restore their bodies after a failed alchemical experiment. The show is filled with action-packed battles, magical elements, and a rich fantasy world. The brothers' journey is filled with adventure as they encounter various allies and enemies along the way.

  • Looking for an anime with adventure, action, and fantasy elements.

    One anime that fits this criteria is "Fullmetal Alchemist: Brotherhood." It follows the journey of two brothers, Edward and Alphonse Elric, as they search for the Philosopher's Stone to restore their bodies after a failed alchemical experiment. The series is filled with action-packed battles, magical elements, and a rich fantasy world. The story is engaging, with well-developed characters and a mix of adventure and fantasy themes that will keep viewers hooked from start to finish.

  • What are some examples of action, adventure, comedy, and fantasy anime?

    Some examples of action anime include "Attack on Titan," "Naruto," and "One Piece." For adventure anime, "Hunter x Hunter," "One Piece," and "Made in Abyss" are popular choices. When it comes to comedy anime, "One Punch Man," "Gintama," and "The Devil is a Part-Timer!" are well-known series. Lastly, for fantasy anime, "Fullmetal Alchemist," "Sword Art Online," and "Fairy Tail" are widely enjoyed by fans.

  • Does Disney Plus have a trial subscription trial week/trial month?

    Yes, Disney Plus offers a trial subscription for one week. This trial period allows new subscribers to explore the platform and its content before committing to a paid subscription. During the trial week, users can access all of Disney Plus's movies, TV shows, and original content. After the trial period ends, the subscription will automatically renew and the user will be charged the monthly fee unless they cancel before the trial ends.

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  • The Trial
    The Trial

    ‘Pacy, dark and highly entertaining, with a real sense of menace’ Sunday Times bestseller, T.M.Logan ‘The very definition of a white-knuckle ride’ Sunday Times bestseller, B P Walter ‘Brilliant . . . a proper page-turner’ Sunday Times bestseller, Laura Marshall Would you sign up to a medical trial if you didn’t know the possible side effects? 18-40? PAID CLINICAL TRIAL IN THE CANARY ISLANDS – UP TO £20,000 TAX FREE It seems like the opportunity of a lifetime.An all-inclusive luxury trip abroad, all you need to do is take a pill every day and keep a diary. Except you don’t know anything about the drug or what its side effects might be. The headaches start, a dull ache at first.Every day worse than the last. Then a body is found. Everyone is a suspect. Anyone could be a killer. Even you . . . The up-all-night thriller perfect for fans of Alex Michaelides, T.M. Logan and JP Delaney Early readers have signed up for The Trial . . . will you? ‘Such a cool premise . . . a page-turner that kept me gripped’ Egan Hughes ‘Full of twists and turns . . . a wild ride I didn’t want to end’ Vanessa Savage ‘Had me not only staying up late to read, but for the first time ever, waking up early too’ Fliss Chester, author of the Fen Churche Mysteries ‘A claustrophobic journey that will have you constantly reevalauting what, and more importantly who, you can put your faith in.Messed with the mind in all the right ways’ Robert Scragg, author of the Porter & Styles series ‘A tantalising premise, this wholly engaging suspense delivers in droves . . . a first-class thrill ride’ ????? NetGalley Reviewer ‘I was sucked in from the beginning and didn’t put it down.What a wild ride’ ????? ‘An ending you won’t see coming . . . shock worthy’ ???? ‘Seriously intense . . . will have you racing through the pages’ ???? ‘Drew me in immediately’ ???? ‘Interestingly real and scary concept . . . it kept me so engrossed’ ???? ‘Intriguing with lots of suspense . . . the explosive climax had my heart racing’ ???? ‘Brilliant concept . . . a captivating read’ Reader Review

    Price: 8.99 £ | Shipping*: 3.99 £
  • Trial Run
    Trial Run

    Discover the classic mystery from Dick Francis, one of the greatest thriller writers of all time'Keeps you enthralled all the way through' 5***** Reader Review'Full of intrigue from start to finish.Another Dick Francis success' 5***** Reader Review'Edge-of-your-seat reading' 5***** Reader Review______Ex-steeplechaser Randall Drew is reluctantly off to pre-Olympic games Moscow, as a favour to royalty.One of the blue bloods is destined to compete in the games and there are concerns - both of safety and of scandal - that only Drew, with his racing connections, can clear up. On arriving - speaking no Russian and wishing he were back home - Drew is supposed to identify and contact one Alyosha to clear up the scandal.Instead, he finds himself tailed by the KGB and embroiled in foiling a terrorist plot - or die trying. Home seems an awful long way away - and if he's not careful, he'll be going back in a box . . . Packed with intrigue and hair-raising suspense, Trial Run is just one of the many blockbuster thrillers from legendary crime writer Dick Francis. Praise for Dick Francis:'The narrative is brisk and gripping and the background researched with care . . . the entire story is a pleasure to relish' Scotsman'Dick Francis's fiction has a secret ingredient - his inimitable knack of grabbing the reader's attention on page one and holding it tight until the very end' Sunday Telegraph'Still the master' Racing Post'The master of suspense and intrigue' Country Life

    Price: 10.99 £ | Shipping*: 3.99 £
  • The Trial
    The Trial

    Kafka's gripping work of psychological horror, with a new introduction and notes by Carolin DuttlingerA terrifying psychological trip into the life of one Joseph K., an ordinary man who wakes up one day to find himself accused of a crime he did not commit, a crime whose nature is never revealed to him.Once arrested, he is released, but must report to court on a regular basis--an event that proves maddening, as nothing is ever resolved.As he grows more uncertain of his fate, his personal life--including work at a bank and his relations with his landlady and a young woman who lives next door--becomes increasingly unpredictable.As K. tries to gain control, he succeeds only in accelerating his own excruciating downward spiral.

    Price: 9.99 £ | Shipping*: 3.99 £
  • The Trial
    The Trial

    Orson Welles directs this adaptation of Kafka's nightmarish novel about a man lost in a system of intractable bureaucracy.Josef K (Anthony Perkins), a humble office worker, is arrested suddenly and without any explanation.Not even told of the crime he has supposedly committed, K finds himself on trial for his life by a monolithic judicial system.Once the gears of the state have started turning, K discovers that they are impossible to stop.

    Price: 9.49 £ | Shipping*: 3.99 £
  • Top anime in the genres of action, fantasy, mystery, etc. are being sought.

    Some of the top anime in the action genre include "Attack on Titan," "My Hero Academia," and "One Punch Man." For fantasy, popular choices are "Fullmetal Alchemist: Brotherhood," "Sword Art Online," and "Re:Zero - Starting Life in Another World." In the mystery genre, anime like "Death Note," "Steins;Gate," and "Detective Conan" are highly recommended. These anime are known for their engaging storylines, well-developed characters, and thrilling plot twists, making them favorites among fans of these genres.

  • Top anime in the genres of Action, Fantasy, Mystery, etc. are being sought.

    Some of the top anime in the action genre include "Attack on Titan," "My Hero Academia," and "One Punch Man." For fantasy, popular choices are "Fullmetal Alchemist: Brotherhood," "Sword Art Online," and "Fate/stay night." In the mystery genre, anime like "Death Note," "Detective Conan," and "Erased" are highly recommended. These anime series are known for their engaging storylines, well-developed characters, and thrilling plot twists that keep viewers hooked from start to finish.

  • What are fantasy strategy games?

    Fantasy strategy games are a genre of video games that combine elements of fantasy and strategy. Players typically take on the role of a leader or commander in a fictional world, where they must make strategic decisions to build and manage their own empire, army, or civilization. These games often involve resource management, tactical combat, and diplomatic relations with other factions or players. Fantasy elements such as magic, mythical creatures, and epic quests are also commonly featured in these games, adding an extra layer of depth and immersion to the gameplay.

  • What is true about Adventure Survival?

    Adventure Survival is a type of outdoor activity that involves learning and practicing survival skills in natural environments. Participants are taught essential skills such as building shelters, finding food and water, navigation, and first aid. This type of activity is often led by experienced guides who provide instruction and ensure the safety of participants. Adventure Survival can be a challenging and rewarding experience that promotes self-reliance, teamwork, and a deeper connection to nature.

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